What will you learn on this course?
This course is an introduction to mass spectral interpretation presenting the fundamental tools and rules when interpreting full-scan LC-MS data. The delegates will benefit from a greater understanding of how to interpret the mass spectra produced by Electrospray Ionisation (ESI) and Atmospheric Pressure Chemical Ionisation (APCI).
The course uses a combination of classroom-based presentations to introduce the theory with a high proportion of tutor-supported tutorial exercises on LC-MS spectral data to facilitate and reinforce the learning process.
If you wish to learn the fundamentals of LC-MS mass spectral interpretation for the identification of unknowns or to enhance your understanding of fragmentation patterns, to assist in accurate identification when using library search programs, then this course is for you.
Who is this course for?
This course is recommended for those who have a good background in organic chemistry and at least six months experience as a LC-MS operator, and is interested in structural elucidation of compounds amenable to analysis by LC-MS.
Learning outcomes:
- You will learn the fundamentals of Electrospray Ionisation (ESI) and Atmospheric Pressure Chemical Ionisation (APCI) mass spectral interpretation for LC-MS
- You will learn how to obtain high quality mass spectra and its importance
- You will learn how electron ionisation occurs and review isotopes and isomers
- You will learn simple techniques to recognise and elucidate spectra
- You will learn how to observe fragmentation patterns for low molecular and high molecular weight molecules
- You will learn about the formation of common adduct ions under different solvent and buffer conditions
- You will learn how to use advanced tools to interpret spectra such as molecular ion, nitrogen rules, degree of unsaturation and losses
- You will learn the importance of alpha and inductive cleavages and rearrangements
Course Discount: All CAMS, HEaTED and RSC members can claim a 15% discount on this course! PhD students can also attend this course as part of our PhD bundle, please visit our website for more information.
This course has been approved by the 萝莉社 for purposes of Continuing Professional Development (CPD).
